Systems Biology: Computational and Mathematical Methods

by E. Mjolsness, P. Baldi, and B. Shapiro

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Chapter 3: Emergent Properties of Small Networks

Supplementary Material

Electronic Notebooks

Exercises

  • Emergent dynamics
  • MAPK exercises

Figures - electronic sources

  • MAPK cascade and transfer function
  • Asp Thr biosynthesis
  • elementary behaviors
  • Brusselator (Figure 3.13c) model file and pdf.
  • feedback loop nullclines
  • repressilator oscillations
  • MAPK with feedback transfer functions
  • stochastic MAPK
  • scaffolded MAPK

Bibliography - electronic access - chapter 3

Text Outline

  • 3.1 Network behavior
  • 3.2 Elementary network analysis
  • 3.3 Small network examples: S-E-P, MAPK, and threonine metabolism
  • 3.4 Dynamical consequences of feedback
  • 3.5 Building larger networks: MAPK in depth
  • 3.6 Summary

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